Network pharmacology-based strategy to investigate pharmacological mechanisms of polysaccharide-free Lycium barbarum extract for chronic kidney disease treatment and verification in an animal model

Network pharmacology-based strategy to investigate pharmacological mechanisms of polysaccharide-free Lycium barbarum extract for chronic kidney disease treatment and verification in an animal model

Lycium barbarum polysaccharides (LBP) have shown renal protection effects. However, research on other active components of L. barbarum extract (ELB) for the therapy of chronic kidney disease (CKD) is limited. This study aims to investigate the renoprotective effects and molecular mechanisms of ELB i...

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Bibliographic Details
Main Authors: Meiyou Liu, Kai Gao, Jia Cui, Xiaoxiao Wu, Likun Ding, Tingting Fan, Juanli Zhang, Di Zhang, Danjun Ren, Aidong Wen, Jingwen Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Renal Failure
Subjects:
Lycium barbarum
chronic kidney diseases
network pharmacology
IL-6
VEGF
Online Access:https://www.tandfonline.com/doi/10.1080/0886022X.2025.2539942
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https://www.tandfonline.com/doi/10.1080/0886022X.2025.2539942

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