THE DIAGNOSTIC EFFICACY AND SAFETY OF MACROCYCLIC GADOLINIUM-BASED MAGNETIC RESONANCE CONTRAST AGENTS
The paper provides information on the safety and diagnostic efficacy of macrocyclic magnetic resonance contrast agents, such as gadobutrol, gadoteridol, and gadoteric acid. It is concluded that the standard gadobutrol dose of 0.1 mmol/kg body weight has a favorable safety profile and is well tolerat...
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| Format: | Article |
| Language: | English |
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Luchevaya Diagnostika, LLC
2017-07-01
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| Series: | Вестник рентгенологии и радиологии |
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| Online Access: | https://www.russianradiology.ru/jour/article/view/235 |
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| author | V. O. Panov N. L. Shimanovskiy |
| author_facet | V. O. Panov N. L. Shimanovskiy |
| author_sort | V. O. Panov |
| collection | DOAJ |
| description | The paper provides information on the safety and diagnostic efficacy of macrocyclic magnetic resonance contrast agents, such as gadobutrol, gadoteridol, and gadoteric acid. It is concluded that the standard gadobutrol dose of 0.1 mmol/kg body weight has a favorable safety profile and is well tolerated by children, including by newborn infants and adults. Owing to the increased relaxivity and double concentration of gadolinium, gadobutrol, as compared to gadoteridol and gadoteric acid, has a higher diagnostic efficacy and pharmacoeconomic advantages. |
| format | Article |
| id | doaj-art-84841e20419543c79ae7ca68e05f33c8 |
| institution | Kabale University |
| issn | 0042-4676 2619-0478 |
| language | English |
| publishDate | 2017-07-01 |
| publisher | Luchevaya Diagnostika, LLC |
| record_format | Article |
| series | Вестник рентгенологии и радиологии |
| spelling | doaj-art-84841e20419543c79ae7ca68e05f33c82025-08-20T03:58:45ZengLuchevaya Diagnostika, LLCВестник рентгенологии и радиологии0042-46762619-04782017-07-0198315916610.20862/0042-4676-2017-98-3-159-166179THE DIAGNOSTIC EFFICACY AND SAFETY OF MACROCYCLIC GADOLINIUM-BASED MAGNETIC RESONANCE CONTRAST AGENTSV. O. Panov0N. L. Shimanovskiy1Russian Medical Academy of Continuing Professional Education, Ministry of Health of the RussiaPirogov Russian National Research Medical University, Ministry of Health of the RussiaThe paper provides information on the safety and diagnostic efficacy of macrocyclic magnetic resonance contrast agents, such as gadobutrol, gadoteridol, and gadoteric acid. It is concluded that the standard gadobutrol dose of 0.1 mmol/kg body weight has a favorable safety profile and is well tolerated by children, including by newborn infants and adults. Owing to the increased relaxivity and double concentration of gadolinium, gadobutrol, as compared to gadoteridol and gadoteric acid, has a higher diagnostic efficacy and pharmacoeconomic advantages.https://www.russianradiology.ru/jour/article/view/235gadobutrolgadoteridolgadoteric acidmagnetic resonance imaging |
| spellingShingle | V. O. Panov N. L. Shimanovskiy THE DIAGNOSTIC EFFICACY AND SAFETY OF MACROCYCLIC GADOLINIUM-BASED MAGNETIC RESONANCE CONTRAST AGENTS Вестник рентгенологии и радиологии gadobutrol gadoteridol gadoteric acid magnetic resonance imaging |
| title | THE DIAGNOSTIC EFFICACY AND SAFETY OF MACROCYCLIC GADOLINIUM-BASED MAGNETIC RESONANCE CONTRAST AGENTS |
| title_full | THE DIAGNOSTIC EFFICACY AND SAFETY OF MACROCYCLIC GADOLINIUM-BASED MAGNETIC RESONANCE CONTRAST AGENTS |
| title_fullStr | THE DIAGNOSTIC EFFICACY AND SAFETY OF MACROCYCLIC GADOLINIUM-BASED MAGNETIC RESONANCE CONTRAST AGENTS |
| title_full_unstemmed | THE DIAGNOSTIC EFFICACY AND SAFETY OF MACROCYCLIC GADOLINIUM-BASED MAGNETIC RESONANCE CONTRAST AGENTS |
| title_short | THE DIAGNOSTIC EFFICACY AND SAFETY OF MACROCYCLIC GADOLINIUM-BASED MAGNETIC RESONANCE CONTRAST AGENTS |
| title_sort | diagnostic efficacy and safety of macrocyclic gadolinium based magnetic resonance contrast agents |
| topic | gadobutrol gadoteridol gadoteric acid magnetic resonance imaging |
| url | https://www.russianradiology.ru/jour/article/view/235 |
| work_keys_str_mv | AT vopanov thediagnosticefficacyandsafetyofmacrocyclicgadoliniumbasedmagneticresonancecontrastagents AT nlshimanovskiy thediagnosticefficacyandsafetyofmacrocyclicgadoliniumbasedmagneticresonancecontrastagents AT vopanov diagnosticefficacyandsafetyofmacrocyclicgadoliniumbasedmagneticresonancecontrastagents AT nlshimanovskiy diagnosticefficacyandsafetyofmacrocyclicgadoliniumbasedmagneticresonancecontrastagents |