The Role of Bile Acid Excretion in Atherosclerotic Coronary Artery Disease

The impact of cholesterol and different classes of lipoproteins on the development of coronary artery disease (CAD) has been investigated in extensively during the past 50 years. The cholesterol metabolism is dependent on numerous factors, including dietary fat, fractional absorption of dietary chol...

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Main Authors: Gideon Charach, Alexander Rabinovich, Ori Argov, Moshe Weintraub, Pavel Rabinovich
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:International Journal of Vascular Medicine
Online Access:http://dx.doi.org/10.1155/2012/949672
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author Gideon Charach
Alexander Rabinovich
Ori Argov
Moshe Weintraub
Pavel Rabinovich
author_facet Gideon Charach
Alexander Rabinovich
Ori Argov
Moshe Weintraub
Pavel Rabinovich
author_sort Gideon Charach
collection DOAJ
description The impact of cholesterol and different classes of lipoproteins on the development of coronary artery disease (CAD) has been investigated in extensively during the past 50 years. The cholesterol metabolism is dependent on numerous factors, including dietary fat, fractional absorption of dietary cholesterol, tissue stores of cholesterol, endogenous cholesterol synthesis, and fecal bile excretion. Several studies showed significantly lower amounts of bile acid secretion in adult patients with CAD compared to non-CAD patients. Could it be that the inability to efficiently excrete bile acids may lead to CAD development?
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institution Kabale University
issn 2090-2824
2090-2832
language English
publishDate 2012-01-01
publisher Wiley
record_format Article
series International Journal of Vascular Medicine
spelling doaj-art-847d005f7cab4421a8e80c80c25e0c492025-02-03T05:47:27ZengWileyInternational Journal of Vascular Medicine2090-28242090-28322012-01-01201210.1155/2012/949672949672The Role of Bile Acid Excretion in Atherosclerotic Coronary Artery DiseaseGideon Charach0Alexander Rabinovich1Ori Argov2Moshe Weintraub3Pavel Rabinovich4Department of Internal Medicine “C”, Tel Aviv Sourasky Medical Center, Tel Aviv 64239, IsraelDepartment of Internal Medicine “C”, Tel Aviv Sourasky Medical Center, Tel Aviv 64239, IsraelDepartment of Internal Medicine “C”, Tel Aviv Sourasky Medical Center, Tel Aviv 64239, IsraelDepartment of Internal Medicine “C”, Tel Aviv Sourasky Medical Center, Tel Aviv 64239, IsraelDepartment of Internal Medicine “C”, Tel Aviv Sourasky Medical Center, Tel Aviv 64239, IsraelThe impact of cholesterol and different classes of lipoproteins on the development of coronary artery disease (CAD) has been investigated in extensively during the past 50 years. The cholesterol metabolism is dependent on numerous factors, including dietary fat, fractional absorption of dietary cholesterol, tissue stores of cholesterol, endogenous cholesterol synthesis, and fecal bile excretion. Several studies showed significantly lower amounts of bile acid secretion in adult patients with CAD compared to non-CAD patients. Could it be that the inability to efficiently excrete bile acids may lead to CAD development?http://dx.doi.org/10.1155/2012/949672
spellingShingle Gideon Charach
Alexander Rabinovich
Ori Argov
Moshe Weintraub
Pavel Rabinovich
The Role of Bile Acid Excretion in Atherosclerotic Coronary Artery Disease
International Journal of Vascular Medicine
title The Role of Bile Acid Excretion in Atherosclerotic Coronary Artery Disease
title_full The Role of Bile Acid Excretion in Atherosclerotic Coronary Artery Disease
title_fullStr The Role of Bile Acid Excretion in Atherosclerotic Coronary Artery Disease
title_full_unstemmed The Role of Bile Acid Excretion in Atherosclerotic Coronary Artery Disease
title_short The Role of Bile Acid Excretion in Atherosclerotic Coronary Artery Disease
title_sort role of bile acid excretion in atherosclerotic coronary artery disease
url http://dx.doi.org/10.1155/2012/949672
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