The Role of Bile Acid Excretion in Atherosclerotic Coronary Artery Disease
The impact of cholesterol and different classes of lipoproteins on the development of coronary artery disease (CAD) has been investigated in extensively during the past 50 years. The cholesterol metabolism is dependent on numerous factors, including dietary fat, fractional absorption of dietary chol...
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Format: | Article |
Language: | English |
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Wiley
2012-01-01
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Series: | International Journal of Vascular Medicine |
Online Access: | http://dx.doi.org/10.1155/2012/949672 |
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author | Gideon Charach Alexander Rabinovich Ori Argov Moshe Weintraub Pavel Rabinovich |
author_facet | Gideon Charach Alexander Rabinovich Ori Argov Moshe Weintraub Pavel Rabinovich |
author_sort | Gideon Charach |
collection | DOAJ |
description | The impact of cholesterol and different classes of lipoproteins on the development of coronary artery disease (CAD) has been investigated in extensively during the past 50 years. The cholesterol metabolism is dependent on numerous factors, including dietary fat, fractional absorption of dietary cholesterol, tissue stores of cholesterol, endogenous cholesterol synthesis, and fecal bile excretion. Several studies showed significantly lower amounts of bile acid secretion in adult patients with CAD compared to non-CAD patients. Could it be that the inability to efficiently excrete bile acids may lead to CAD development? |
format | Article |
id | doaj-art-847d005f7cab4421a8e80c80c25e0c49 |
institution | Kabale University |
issn | 2090-2824 2090-2832 |
language | English |
publishDate | 2012-01-01 |
publisher | Wiley |
record_format | Article |
series | International Journal of Vascular Medicine |
spelling | doaj-art-847d005f7cab4421a8e80c80c25e0c492025-02-03T05:47:27ZengWileyInternational Journal of Vascular Medicine2090-28242090-28322012-01-01201210.1155/2012/949672949672The Role of Bile Acid Excretion in Atherosclerotic Coronary Artery DiseaseGideon Charach0Alexander Rabinovich1Ori Argov2Moshe Weintraub3Pavel Rabinovich4Department of Internal Medicine “C”, Tel Aviv Sourasky Medical Center, Tel Aviv 64239, IsraelDepartment of Internal Medicine “C”, Tel Aviv Sourasky Medical Center, Tel Aviv 64239, IsraelDepartment of Internal Medicine “C”, Tel Aviv Sourasky Medical Center, Tel Aviv 64239, IsraelDepartment of Internal Medicine “C”, Tel Aviv Sourasky Medical Center, Tel Aviv 64239, IsraelDepartment of Internal Medicine “C”, Tel Aviv Sourasky Medical Center, Tel Aviv 64239, IsraelThe impact of cholesterol and different classes of lipoproteins on the development of coronary artery disease (CAD) has been investigated in extensively during the past 50 years. The cholesterol metabolism is dependent on numerous factors, including dietary fat, fractional absorption of dietary cholesterol, tissue stores of cholesterol, endogenous cholesterol synthesis, and fecal bile excretion. Several studies showed significantly lower amounts of bile acid secretion in adult patients with CAD compared to non-CAD patients. Could it be that the inability to efficiently excrete bile acids may lead to CAD development?http://dx.doi.org/10.1155/2012/949672 |
spellingShingle | Gideon Charach Alexander Rabinovich Ori Argov Moshe Weintraub Pavel Rabinovich The Role of Bile Acid Excretion in Atherosclerotic Coronary Artery Disease International Journal of Vascular Medicine |
title | The Role of Bile Acid Excretion in Atherosclerotic Coronary Artery Disease |
title_full | The Role of Bile Acid Excretion in Atherosclerotic Coronary Artery Disease |
title_fullStr | The Role of Bile Acid Excretion in Atherosclerotic Coronary Artery Disease |
title_full_unstemmed | The Role of Bile Acid Excretion in Atherosclerotic Coronary Artery Disease |
title_short | The Role of Bile Acid Excretion in Atherosclerotic Coronary Artery Disease |
title_sort | role of bile acid excretion in atherosclerotic coronary artery disease |
url | http://dx.doi.org/10.1155/2012/949672 |
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