Barriers to transmission of transcriptional noise in a c‐fos c‐jun pathway

Abstract We explored how transcriptional noise propagates in gene‐regulatory pathways by studying the induction of two downstream genes by transcription factors c‐fos and c‐jun. They are produced for a brief period following serum stimulation of cells and then activate the promoters of their target...

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Bibliographic Details
Main Authors: Khyati Shah, Sanjay Tyagi
Format: Article
Language:English
Published: Springer Nature 2013-09-01
Series:Molecular Systems Biology
Subjects:
Online Access:https://doi.org/10.1038/msb.2013.45
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