HIC1 suppresses Tumor Progression and Enhances CD8+ T Cells Infiltration Through Promoting GSDMD‐induced Pyroptosis in Gastric Cancer

HIC1 suppresses Tumor Progression and Enhances CD8+ T Cells Infiltration Through Promoting GSDMD‐induced Pyroptosis in Gastric Cancer

Abstract Recently, immune checkpoint blockade treatment has made remarkable strides in combatting malignancies, including gastric cancer (GC). Nonetheless, the efficacy of immunotherapy in GC patients remains constrained, warranting further exploration of the underlying molecular mechanisms to impro...

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Bibliographic Details
Main Authors: Mengjie Kang, Wenqi Du, Lina Ding, Mengdi Wu, Dongsheng Pei
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:Advanced Science
Subjects:
cell pyroptosis
gastric cancer
GSDMD
HIC1
immune infiltration
Online Access:https://doi.org/10.1002/advs.202412083
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