Role of paraoxonase 2 (PON2) as a potential biomarker and therapeutic target in cancer treatment
Abstract Purpose Paraoxonase 2 (PON2), a mitochondrial antioxidant enzyme, is widely expressed across body tissues and plays vital roles in cellular defence. Growing evidence links its dysregulation to oxidative stress and cancer progression. This narrative review aims to elucidate PON2’s enzymatic...
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| Main Authors: | Vinayak Agarwal, Matthew Cheesman, Alison Haywood, Sohil Khan, Shailendra Anoopkumar Dukie |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer
2025-08-01
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| Series: | Journal of Cancer Research and Clinical Oncology |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/s00432-025-06282-y |
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