NQO1 antagonizes PM2.5-induced apoptosis of Sertoli cells by activating the UPRmt pathway
The mechanism by which NQO1 antagonizes PM2.5-induced apoptosis in Sertoli cells through activation of the mitochondrial unfolded protein response (UPRmt) was investigated. A reproductive toxicity model was established using TM4 cells exposed to PM2.5 (50 μg/mL, 24 h). Transcriptome sequencing and b...
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| Main Authors: | Cao Wang, Qing Xiao, Mingchen Xiao, Yu Chu, Yaya Ai, Zhen Luo, Guangxu Zhou, Kaiyi Mao, Bin Liu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-09-01
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| Series: | Ecotoxicology and Environmental Safety |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0147651325010747 |
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