The Adeno-Associated Virus Replication Protein Rep78 Contains a Strictly C-Terminal Sequence Motif Conserved Across Dependoparvoviruses

Adeno-Associated Viruses (AAVs, genus <i>Dependoparvovirus</i>) are the leading gene therapy vector. Until recently, efforts to enhance their capacity for gene delivery had focused on their capsids. However, efforts are increasingly shifting towards improving the viral replication protei...

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Bibliographic Details
Main Author: David G. Karlin
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/16/11/1760
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