Microbiota dysbiosis influences immune system and muscle pathophysiology of dystrophin‐deficient mice

Microbiota dysbiosis influences immune system and muscle pathophysiology of dystrophin‐deficient mice

Abstract Duchenne muscular dystrophy (DMD) is a progressive severe muscle‐wasting disease caused by mutations in DMD, encoding dystrophin, that leads to loss of muscle function with cardiac/respiratory failure and premature death. Since dystrophic muscles are sensed by infiltrating inflammatory cell...

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Main Authors: Andrea Farini, Luana Tripodi, Chiara Villa, Francesco Strati, Amanda Facoetti, Guido Baselli, Jacopo Troisi, Annamaria Landolfi, Caterina Lonati, Davide Molinaro, Michelle Wintzinger, Stefano Gatti, Barbara Cassani, Flavio Caprioli, Federica Facciotti, Mattia Quattrocelli, Yvan Torrente
Format: Article
Language:English
Published: Springer Nature 2022-12-01
Series:EMBO Molecular Medicine
Subjects:
Duchenne muscular dystrophy
gut microbiota
immunity
skeletal muscle metabolism
T‐lymphocytes
Online Access:https://doi.org/10.15252/emmm.202216244
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https://doi.org/10.15252/emmm.202216244

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