Biochemical and physiological characterization of Aedes aegypti midgut chymotrypsin

Biochemical and physiological characterization of Aedes aegypti midgut chymotrypsin

Abstract The Aedes aegypti mosquito is a vector of dengue, Zika, and chikungunya. The mosquito’s reliance on blood facilitates the transmission of these viral pathogens to humans. Digestion of blood proteins depends on the biphasic expression of serine proteases, with trypsin-like activity contribut...

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Main Authors: Abigail G. Ramirez, Jun Isoe, Mateus Sá Magalhães Serafim, Daniel Fong, My Anh Le, James T. Nguyen, Olive E. Burata, Rachael M. Lucero, Rebecca K. Spangler, Alberto A. Rascón
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Subjects:
Chymotrypsin
RNA interference (RNAi)
Enzyme kinetics
Blood meal digestion
Aedes aegypti
Vector control
Online Access:https://doi.org/10.1038/s41598-025-93413-7
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https://doi.org/10.1038/s41598-025-93413-7

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