The multifaceted role of vitreous hyalocytes: Orchestrating inflammation, angiomodulation and erythrophagocytosis in proliferative diabetic retinopathy

The multifaceted role of vitreous hyalocytes: Orchestrating inflammation, angiomodulation and erythrophagocytosis in proliferative diabetic retinopathy

Abstract Background Despite great advances in proliferative diabetic retinopathy (PDR) therapy over the last decades, one third of treated patients continue to lose vision. While resident vitreous macrophages called hyalocytes have been implicated in the pathophysiology of vitreoretinal proliferativ...

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Main Authors: Stefaniya K. Boneva, Julian Wolf, Malte Jung, Gabriele Prinz, Toco Y. P. Chui, Jacqueline Jauch, Anne Drougard, J. Andrew Pospisilik, Anja Schlecht, Felicitas Bucher, Richard B. Rosen, Hansjürgen Agostini, Günther Schlunck, Clemens A. K. Lange
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Journal of Neuroinflammation
Subjects:
Hyalocytes
Vitreous macrophages
Proliferative diabetic retinopathy
Inflammation
Angiomodulation
Erythrophagocytosis
Online Access:https://doi.org/10.1186/s12974-024-03291-5
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https://doi.org/10.1186/s12974-024-03291-5

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