Laboratory readiness and genomic surveillance of Covid-19 in the capital of Brazil.
This study aims to analyze the diagnostic readiness to Covid-19 and the genomic surveillance of SARS-CoV-2 in Brasília, the capital of Brazil. This is a retrospective, cross-sectional study, with data from: cases/deaths-Ministry of Health; RT-PCR analyses Brasília Central Public Health Laboratory (L...
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2025-01-01
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| Series: | PLOS Global Public Health |
| Online Access: | https://doi.org/10.1371/journal.pgph.0003289 |
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| author | Fabrício Vieira Cavalcante Christina Pacheco Santos Martin Gustavo Saraiva Frio Rodrigo Guerino Stabeli Leonor Maria Pacheco Santos |
| author_facet | Fabrício Vieira Cavalcante Christina Pacheco Santos Martin Gustavo Saraiva Frio Rodrigo Guerino Stabeli Leonor Maria Pacheco Santos |
| author_sort | Fabrício Vieira Cavalcante |
| collection | DOAJ |
| description | This study aims to analyze the diagnostic readiness to Covid-19 and the genomic surveillance of SARS-CoV-2 in Brasília, the capital of Brazil. This is a retrospective, cross-sectional study, with data from: cases/deaths-Ministry of Health; RT-PCR analyses Brasília Central Public Health Laboratory (LACEN); genomics-Global Initiative on Sharing All Influenza Data (GISAID). It was found that in March 2021, with the Gamma variant was predominant, RT-PCR diagnostic tests administered by LACEN reached their peak, followed by a reduction, possibly due to the start of vaccination. New peaks were observed in September 2021 and January 2022. The average time for releasing RT-PCR results was reduced from eight days (July 2020), to around eight hours in 2023. The participation of private laboratories was evident in sequencing the SARS-CoV-2 variants of concern in Brasília (n = 1,897). LACEN sequenced 50% of the samples received (571). A decrease in the incidence of cases and deaths due to Covid-19 was noted in the years 2022 to 2023, following the national trend. LACEN maintained RT-PCR diagnostic tests administered satisfactorily throughout the period. Regarding the genomic surveillance of SARS-CoV-2, the vast majority of samples were sequenced by private laboratories when compared to the public laboratory. |
| format | Article |
| id | doaj-art-8156f996fbe24f0ba130922a9769a547 |
| institution | Kabale University |
| issn | 2767-3375 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLOS Global Public Health |
| spelling | doaj-art-8156f996fbe24f0ba130922a9769a5472025-01-17T05:49:09ZengPublic Library of Science (PLoS)PLOS Global Public Health2767-33752025-01-0151e000328910.1371/journal.pgph.0003289Laboratory readiness and genomic surveillance of Covid-19 in the capital of Brazil.Fabrício Vieira CavalcanteChristina Pacheco Santos MartinGustavo Saraiva FrioRodrigo Guerino StabeliLeonor Maria Pacheco SantosThis study aims to analyze the diagnostic readiness to Covid-19 and the genomic surveillance of SARS-CoV-2 in Brasília, the capital of Brazil. This is a retrospective, cross-sectional study, with data from: cases/deaths-Ministry of Health; RT-PCR analyses Brasília Central Public Health Laboratory (LACEN); genomics-Global Initiative on Sharing All Influenza Data (GISAID). It was found that in March 2021, with the Gamma variant was predominant, RT-PCR diagnostic tests administered by LACEN reached their peak, followed by a reduction, possibly due to the start of vaccination. New peaks were observed in September 2021 and January 2022. The average time for releasing RT-PCR results was reduced from eight days (July 2020), to around eight hours in 2023. The participation of private laboratories was evident in sequencing the SARS-CoV-2 variants of concern in Brasília (n = 1,897). LACEN sequenced 50% of the samples received (571). A decrease in the incidence of cases and deaths due to Covid-19 was noted in the years 2022 to 2023, following the national trend. LACEN maintained RT-PCR diagnostic tests administered satisfactorily throughout the period. Regarding the genomic surveillance of SARS-CoV-2, the vast majority of samples were sequenced by private laboratories when compared to the public laboratory.https://doi.org/10.1371/journal.pgph.0003289 |
| spellingShingle | Fabrício Vieira Cavalcante Christina Pacheco Santos Martin Gustavo Saraiva Frio Rodrigo Guerino Stabeli Leonor Maria Pacheco Santos Laboratory readiness and genomic surveillance of Covid-19 in the capital of Brazil. PLOS Global Public Health |
| title | Laboratory readiness and genomic surveillance of Covid-19 in the capital of Brazil. |
| title_full | Laboratory readiness and genomic surveillance of Covid-19 in the capital of Brazil. |
| title_fullStr | Laboratory readiness and genomic surveillance of Covid-19 in the capital of Brazil. |
| title_full_unstemmed | Laboratory readiness and genomic surveillance of Covid-19 in the capital of Brazil. |
| title_short | Laboratory readiness and genomic surveillance of Covid-19 in the capital of Brazil. |
| title_sort | laboratory readiness and genomic surveillance of covid 19 in the capital of brazil |
| url | https://doi.org/10.1371/journal.pgph.0003289 |
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