The augmentative role of chitosan and platelet-rich fibrin in reducing epidural fibrosis after laminectomy in rats

The augmentative role of chitosan and platelet-rich fibrin in reducing epidural fibrosis after laminectomy in rats

Abstract Background Epidural fibrosis (EF) is the major complication that develops in the operative region of the spinal vertebrae. This fibrous scar connects the connective tissue around the lateral nerve roots and epidural, resulting in severe pain post-spinal operation and impairment of the nerve...

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Main Authors: Samah Fouad, Marwa Abass, Awad Rizk, Esam Mosbah, Mostafa M. Nabeeh, Ayman S. Elmezayyen, M. I. El-Henawey, Adel Zaghloul
Format: Article
Language:English
Published: BMC 2025-08-01
Series:European Journal of Medical Research
Subjects:
Chitosan
Platelets-rich fibrin
Laminectomy
Epidural fibrosis
Online Access:https://doi.org/10.1186/s40001-025-02951-3
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https://doi.org/10.1186/s40001-025-02951-3

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