Structure and post-translational modification of the prostaglandin transporter

Abstract The prostaglandin transporter (PGT) is a member of the OATP family of membrane transporters. PGT mediates the uptake of prostaglandins from the extracellular environment to enable intracellular enzymatic degradation and termination of signaling. In addition to importing prostaglandins, PGT...

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Bibliographic Details
Main Authors: Peixuan Yu, Melanie A. Orlando, Benjamin J. Orlando
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08510-0
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