Enhanced differentiation of neural progenitor cells in Alzheimer’s disease into vulnerable immature neurons

Enhanced differentiation of neural progenitor cells in Alzheimer’s disease into vulnerable immature neurons

Summary: Focusing on the early stages of Alzheimer’s disease (AD) holds great promise. However, the specific events in neural cells preceding AD onset remain elusive. To address this, we utilized human-induced pluripotent stem cells carrying APPswe mutation to explore the initial changes associated...

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Bibliographic Details
Main Authors: Joonho Cho, Simsung Bae, Juyeong Jeon, Janis Transfeld, Changyeob Lee, Alexi Nott, Fan Gao, Jinsoo Seo
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:iScience
Subjects:
molecular biology
neuroscience
cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225007072
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