In situ size amplification strategy reduces lymphatic clearance for enhanced arthritis therapy

Abstract Rheumatoid arthritis (RA) is an autoimmune disorder characterized by painful swelling and inflammation, arising from the immune system attacking on healthy cells. However, arthritic sites often experience increased lymph flow, hastening drug clearance and potentially reducing treatment effe...

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Bibliographic Details
Main Authors: Xianyan Qin, Luhan Zhang, Yang-Bao Miao, Linxi Jiang, Liang Zou, Qin Wang, Yi Shi
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Journal of Nanobiotechnology
Subjects:
Online Access:https://doi.org/10.1186/s12951-024-03061-8
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