CXCR6 expression predicts prognosis and immunotherapeutic benefit in muscle-invasive bladder cancer

CXCR6 expression predicts prognosis and immunotherapeutic benefit in muscle-invasive bladder cancer

BackgroundIncreasing evidence suggests that the CXC chemokine receptor 6 (CXCR6) is involved in tumor progression and the regulation of tumor immunity. However, its role in muscle-invasive bladder cancer (MIBC) remains largely unexplored.MethodsData from 391 MIBC patients in the TCGA, 212 patients f...

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Bibliographic Details
Main Authors: Xiaolin Lu, Li-Ping Ge, Zhaopei Liu, Yu Zhu, Dingwei Ye, Yuan Chang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Oncology
Subjects:
muscle-invasive bladder cancer
CXCR6
tumor immune microenvironment
prognostic biomarker
immunotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1498579/full
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