Novel Fast-Setting and Mechanically-Strong Calcium Phosphate Pulp-Capping Cement with Metformin Release to Enhance Dental Pulp Stem Cells

Novel Fast-Setting and Mechanically-Strong Calcium Phosphate Pulp-Capping Cement with Metformin Release to Enhance Dental Pulp Stem Cells

Traditional pulp-capping materials like mineral trioxide aggregate (MTA) offer excellent biocompatibility and sealing, but limitations such as prolonged setting time, low bioactivity, and high costs persist. Metformin, with its potential in craniofacial regeneration, could enhance dentin synthesis b...

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Bibliographic Details
Main Authors: Mohammad Alenizy, Abdullah Alhussein, Nader Almutairi, Ibrahim Ba-Armah, Tao Ma, Suping Wang, Nageswara R. Pilli, Maureen A. Kane, Michael D. Weir, Abraham Schneider, Hockin H. K. Xu
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Bioengineering
Subjects:
dentin regeneration
direct pulp capping
bioactive material
chitosan
metformin
biocompatibility
Online Access:https://www.mdpi.com/2306-5354/12/1/13
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