Toll-like receptor 3 signaling attenuated colitis-associated cancer development in mice
Abstract Inflammatory bowel disease is associated with a high risk of colitis-associated cancer (CAC). We evaluated the role of TLR3 in CAC using a murine model. Wild-type (WT) and TLR3-knockout (TLR3−/−) mice received azoxymethane (AOM) 12.5 mg/kg intraperitoneally on day zero, followed by three cy...
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| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2024-12-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-024-76954-1 |
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