Combined metabolic engineering and lipid droplets degradation to increase vitamin A production in Saccharomyces cerevisiae

Abstract Background In microbial cell factories, substrate accessibility to enzyme is a key factor affecting the biosynthesis of natural products. As a robust chassis cells for biofuels and bioproducts, Saccharomyces cerevisiae also encounters the challenge since different enzymes and precursors are...

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Bibliographic Details
Main Authors: Jing-Yuan Lin, Xiao Bu, Yi-Bin Lan, Chang-Qing Duan, Guo-Liang Yan
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Microbial Cell Factories
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Online Access:https://doi.org/10.1186/s12934-024-02596-7
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