Curcumin nanocrystals ameliorate ferroptosis of diabetic nephropathy through glutathione peroxidase 4

Curcumin nanocrystals ameliorate ferroptosis of diabetic nephropathy through glutathione peroxidase 4

ObjectiveThe aim of this study was to investigate the effect of curcumin nanocrystals (Cur-NCs) on ferroptosis in high-glucose (HG)-induced HK-2 cells and streptozotocin (STZ)-induced diabetic nephropathy model (DN) rats. The purpose is to determine whether Cur NCs can become a promising treatment o...

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Bibliographic Details
Main Authors:	Mengjiao Xue, Yiwei Tian, Hua Zhang, Shijie Dai, Yangsheng Wu, Juan Jin, Jian Chen
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-01-01
Series:	Frontiers in Pharmacology
Subjects:	curcumin nanocrystals ferroptosis diabetic nephropathy GPX4
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2024.1508312/full
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