A Meta-Analysis of Tea Drinking and Risk of Parkinson's Disease
Background. Many studies have reported an association between tea drinking and Parkinson's disease (PD). Our purpose is to summarize the available information and evaluate the risk of PD associated with tea drinking. Methods. We searched all publications in English language on the association o...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1100/2012/923464 |
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| _version_ | 1841524468534476800 |
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| author | Feng-Jiao Li Hong-Fang Ji Liang Shen |
| author_facet | Feng-Jiao Li Hong-Fang Ji Liang Shen |
| author_sort | Feng-Jiao Li |
| collection | DOAJ |
| description | Background. Many studies have reported an association between tea drinking and Parkinson's disease (PD). Our purpose is to summarize the available information and evaluate the risk of PD associated with tea drinking. Methods. We searched all publications in English language on the association of tea drinking and PD risk published up to December 2010. The pooled analysis was performed with Review Manager 5.0. Results. In total, eight articles including 1418 cases and 4250 controls were included in the meta-analysis. The pooled odds ratio (95% CI) was 0.85 (0.74–0.98), which suggests the protective effect of tea drinking in PD risks. Moreover, the summary OR (OR: 0.83, 95% CI = 0.69–0.99) for drinkers of ≤1 cup of tea per day versus nonconsumers and that (OR: 0.96, 95% CI = 0.73–1.27) for drinkers of >1 cups of tea per day versus nonconsumers showed that there was not an apparent dose-response relationship. No indication for publication bias was found. Conclusions. This meta-analysis showed that tea drinking can lower the risk of PD, while no apparent dose-response relationship was found. Further effort is needed to fully understand the mechanism underlying the beneficial effect of tea consumption in lowering PD risk. |
| format | Article |
| id | doaj-art-800dfcfa29144a6a911e6284040b756e |
| institution | Kabale University |
| issn | 1537-744X |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-800dfcfa29144a6a911e6284040b756e2025-02-03T05:53:03ZengWileyThe Scientific World Journal1537-744X2012-01-01201210.1100/2012/923464923464A Meta-Analysis of Tea Drinking and Risk of Parkinson's DiseaseFeng-Jiao Li0Hong-Fang Ji1Liang Shen2Shandong Provincial Research Center for Bioinformatic Engineering and Technique, Shandong University of Technology, Zibo 255049, ChinaShandong Provincial Research Center for Bioinformatic Engineering and Technique, Shandong University of Technology, Zibo 255049, ChinaShandong Provincial Research Center for Bioinformatic Engineering and Technique, Shandong University of Technology, Zibo 255049, ChinaBackground. Many studies have reported an association between tea drinking and Parkinson's disease (PD). Our purpose is to summarize the available information and evaluate the risk of PD associated with tea drinking. Methods. We searched all publications in English language on the association of tea drinking and PD risk published up to December 2010. The pooled analysis was performed with Review Manager 5.0. Results. In total, eight articles including 1418 cases and 4250 controls were included in the meta-analysis. The pooled odds ratio (95% CI) was 0.85 (0.74–0.98), which suggests the protective effect of tea drinking in PD risks. Moreover, the summary OR (OR: 0.83, 95% CI = 0.69–0.99) for drinkers of ≤1 cup of tea per day versus nonconsumers and that (OR: 0.96, 95% CI = 0.73–1.27) for drinkers of >1 cups of tea per day versus nonconsumers showed that there was not an apparent dose-response relationship. No indication for publication bias was found. Conclusions. This meta-analysis showed that tea drinking can lower the risk of PD, while no apparent dose-response relationship was found. Further effort is needed to fully understand the mechanism underlying the beneficial effect of tea consumption in lowering PD risk.http://dx.doi.org/10.1100/2012/923464 |
| spellingShingle | Feng-Jiao Li Hong-Fang Ji Liang Shen A Meta-Analysis of Tea Drinking and Risk of Parkinson's Disease The Scientific World Journal |
| title | A Meta-Analysis of Tea Drinking and Risk of Parkinson's Disease |
| title_full | A Meta-Analysis of Tea Drinking and Risk of Parkinson's Disease |
| title_fullStr | A Meta-Analysis of Tea Drinking and Risk of Parkinson's Disease |
| title_full_unstemmed | A Meta-Analysis of Tea Drinking and Risk of Parkinson's Disease |
| title_short | A Meta-Analysis of Tea Drinking and Risk of Parkinson's Disease |
| title_sort | meta analysis of tea drinking and risk of parkinson s disease |
| url | http://dx.doi.org/10.1100/2012/923464 |
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