Transcriptomic and genetic profiling in a spontaneous non-human primate model of hypertrophic cardiomyopathy and sudden cardiac death

Transcriptomic and genetic profiling in a spontaneous non-human primate model of hypertrophic cardiomyopathy and sudden cardiac death

Abstract Hypertrophic cardiomyopathy (HCM) afflicts humans, cats, pigs, and rhesus macaques. Disease sequelae include congestive heart failure, thromboembolism, and sudden cardiac death (SCD). Sarcomeric mutations explain some human and cat cases, however, the molecular basis in rhesus macaques rema...

Full description

Saved in:
Bibliographic Details
Main Authors: Victor N. Rivas, Michael W. Vandewege, Yu Ueda, Joanna L. Kaplan, JRachel Reader, Jeffrey A. Roberts, Joshua A. Stern
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Scientific Reports
Subjects:
Whole-genome sequencing
RNA-sequencing
Multi-omics
Monkey
Large-animal model
Arrythmia
Online Access:https://doi.org/10.1038/s41598-024-82770-4
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1038/s41598-024-82770-4

Similar Items