Higher levels of plasma phosphatidylcholine (17:0_18:1) raise the risk of developing Parkinson’s disease

Higher levels of plasma phosphatidylcholine (17:0_18:1) raise the risk of developing Parkinson’s disease

Abstract Emerging evidence suggests that dysregulation of lipid metabolism and chronic inflammation in the central nervous system (CNS) contribute to the risk of Parkinson’s disease (PD). However, the causal relationship between plasma lipid metabolism and PD, particularly through immune modulation,...

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Bibliographic Details
Main Authors: Daoqing Su, Yajun Jing, Jinye Su, Honglin Zhu, Yiming Chen, Qiu He, Dengliang Wang, Dezhi Kang, Yuanxiang Lin
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
Lipid metabolism
Parkinson’s disease
Circulating inflammatory proteins
Circulating immune cells
Mendelian randomization analysis
Online Access:https://doi.org/10.1038/s41598-025-12054-y
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https://doi.org/10.1038/s41598-025-12054-y

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