Platelet glycoprotein VI promotes folic acid-induced acute kidney injury through interaction with tubular epithelial cell-derived galectin-3

Platelet glycoprotein VI promotes folic acid-induced acute kidney injury through interaction with tubular epithelial cell-derived galectin-3

Abstract Background Acute kidney injury (AKI) is defined by a significant reduction in renal function, which subsequently impairs coagulation and activates the inflammatory immune response, ultimately resulting in damage to renal tubular epithelial cells (TECs). Platelets are crucial in mediating bo...

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Bibliographic Details
Main Authors: Ya-Wei Guo, Qi Luo, Meng Lu, Xiang-Bin Zeng, Yu-Min Zhang, Yue-Ling Lin, Xu-Ran Guo, Rong Ma, Zhang-Yin Ming
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Cell Communication and Signaling
Subjects:
Platelets
GPVI
Galectin-3
Acute kidney injury
Monocyte-platelet aggregates
Macrophage
Online Access:https://doi.org/10.1186/s12964-025-02148-5
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https://doi.org/10.1186/s12964-025-02148-5

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