Hypotensive effect of bi-potassium salt of 1-hexadecyl-2-methylcarbamoylphosphatidic acid in rats with renovascular hypertension

Hypotensive effect of bi-potassium salt of 1-hexadecyl-2-methylcarbamoylphosphatidic acid in rats with renovascular hypertension

The study describes the synthesis and hypotensive effects of stable platelet activation factor (PAF) precursor 1-hexadecyl-2-m ethylcarbamoyl-phosphatidic acid (HMCP) оn outbred Wistar rats with 1-kidney 1-clip (1K1C) renovascular hypertension. Intravenous injection of 0.1, 0.5, 1 and 5 mg/kg HMCP r...

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Main Authors: N. Y. Khromova, S. I. Malekin, S. A. Gavrilova, S. V. Kotelevtsev, Yu. V. Kotelevtsev
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2018-12-01
Series:Бюллетень сибирской медицины
Subjects:
platelet activation factor (paf)
arterial hypertension
renal hypertension
alkyl acylg lycerol
alkyl acyl phosphatidic acid
1-hexadecyl-2-methylcarbamoyl-phosphatidic acid
Online Access:https://bulletin.ssmu.ru/jour/article/view/1989
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