DNA methylation markers for sensitive detection of circulating tumor DNA in patients with gastroesophageal cancers

DNA methylation markers for sensitive detection of circulating tumor DNA in patients with gastroesophageal cancers

Background: Patients with gastric and gastroesophageal junction adenocarcinomas (G-GEJ ACs) face poor outcomes. Thus sensitive biomarkers for improved clinical management are highly warranted. Detection of circulating tumor DNA (ctDNA) using DNA methylation biomarkers is a highly sensitive approach...

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Main Authors: N. Øgaard, C.R. Iden, S.Ø. Jensen, S.M. Mustafa, E. Aagaard, J.B. Bramsen, L.B. Ahlborn, J.P. Hasselby, K.S. Rohrberg, M.P. Achiam, C.L. Andersen, M. Mau-Sørensen
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:ESMO Gastrointestinal Oncology
Subjects:
esophagus adenocarcinoma
gastric adenocarcinoma
gastroesophageal junction cancer
DNA methylation
circulating tumor DNA
cancer biomarker
Online Access:http://www.sciencedirect.com/science/article/pii/S2949819824000657
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