Loss of chromosome cytoband 13q14.2 orchestrates breast cancer pathogenesis and drug response

Abstract Breast cancer (BCa) is a major global health challenge. The BCa genome often carries extensive somatic copy number alterations (CNAs), including gains/amplifications and losses/deletions. These CNAs significantly affect tumor development, drug response and patient survival. However, how ind...

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Bibliographic Details
Main Authors:	Parastoo Shahrouzi, Youness Azimzade, Wioletta Brankiewicz-Kopcinska, Sugandha Bhatia, David Kunke, Derek Richard, Xavier Tekpli, Vessela N. Kristensen, Pascal H. G. Duijf
Format:	Article
Language:	English
Published:	BMC 2024-11-01
Series:	Breast Cancer Research
Subjects:	Copy number alterations Chromosome 13q14.2 Breast cancer Biomarker Drug sensitivity Tumor microenvironment
Online Access:	https://doi.org/10.1186/s13058-024-01924-4
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Loss of chromosome cytoband 13q14.2 orchestrates breast cancer pathogenesis and drug response

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