Loss of chromosome cytoband 13q14.2 orchestrates breast cancer pathogenesis and drug response

Loss of chromosome cytoband 13q14.2 orchestrates breast cancer pathogenesis and drug response

Abstract Breast cancer (BCa) is a major global health challenge. The BCa genome often carries extensive somatic copy number alterations (CNAs), including gains/amplifications and losses/deletions. These CNAs significantly affect tumor development, drug response and patient survival. However, how ind...

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Main Authors: Parastoo Shahrouzi, Youness Azimzade, Wioletta Brankiewicz-Kopcinska, Sugandha Bhatia, David Kunke, Derek Richard, Xavier Tekpli, Vessela N. Kristensen, Pascal H. G. Duijf
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Breast Cancer Research
Subjects:
Copy number alterations
Chromosome 13q14.2
Breast cancer
Biomarker
Drug sensitivity
Tumor microenvironment
Online Access:https://doi.org/10.1186/s13058-024-01924-4
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https://doi.org/10.1186/s13058-024-01924-4

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