Causal association between matrix metalloproteinases and diabetic neuropathy: a two-sample Mendelian randomization study

Causal association between matrix metalloproteinases and diabetic neuropathy: a two-sample Mendelian randomization study

ObjectiveDiabetic neuropathy (DN), a common and debilitating complication of diabetes, significantly impairs the quality of life of affected individuals. While multiple studies have indicated changes in the expression of specific matrix metalloproteinases (MMPs) in patients with DN, and basic resear...

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Main Authors: Chao Bai, Wenwen Yang, Guangwei Qi, Liuyu Yang, Qingrui Wu, Jieguang Peng, Ning Wang, Tao Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Endocrinology
Subjects:
diabetic neuropathy
Mendelian randomization
MMP-2
MMP-16
GWAS
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2024.1429121/full
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https://www.frontiersin.org/articles/10.3389/fendo.2024.1429121/full

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