The clinical analysis and indications for exchange transfusion in 158 children with pertussis characterized by marked leukocytosis

Abstract Background Hyperleukocytosis (WBC ≥ 30 × 10⁹/L) strongly associated with fatal outcomes; evidence-based thresholds for initiating exchange transfusion (ET) remain undefined. This study aims to investigate the association between leukocyte elevation and disease severity, and define evidence-...

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Bibliographic Details
Main Authors: Gaihuan Zheng, Qing Liu, Chuan Gan
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Italian Journal of Pediatrics
Subjects:
Online Access:https://doi.org/10.1186/s13052-025-02077-6
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