Quantitation of polysorbate 80 in recombinant protein formulation using high-performance liquid chromatography
Objectives. Polysorbate 80 (PS80) quantification in biopharmaceutical products has always been challenging owing to its minute content, absorption to the protein backbone, lack of specific chromophoric PS80 groups, and heterogenic nature. This work is aimed at developing an express method for PS80 a...
Saved in:
| Main Authors: | A. D. Askretkov, D. O. Shatalov, N. V. Orlova, D. I. Zybin, V. V. Nikolaeva, A. A. Klishin, E. S. Tuzova, D. S. Minenkov, S. A. Kedik, Yu. A. Seregin |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
MIREA - Russian Technological University
2022-04-01
|
| Series: | Тонкие химические технологии |
| Subjects: | |
| Online Access: | https://www.finechem-mirea.ru/jour/article/view/1798 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Quantification of polysorbate 80 in biopharmaceutical formulations implementing an optimized colorimetric approach
by: A. S. Seregin, et al.
Published: (2020-07-01) -
DETERMINATION OF POLYSORBATES BY SPECTROPHOTOMETRY IN DRUGS BASED ON RECOMBINANT PROTEINS
by: A. D. Askretkov, et al.
Published: (2019-01-01) -
Colloid-chemical properties of aqueous propolis dispersion prepared by the solvent diffusion method
by: M. Yu. Pletnev, et al.
Published: (2011-08-01) -
Role of Emulsifiers and SPF Booster in Sunscreen Performance: Assessing SPF, Rheological Behavior, Texture, and Stability
by: Miroslava Špaglová, et al.
Published: (2025-06-01) -
Development and validation of a method for the determination of the specific activity of recombinant monoclonal antibody eculizumab
by: D. I. Zybin, et al.
Published: (2020-05-01)