Apyrase decreases phage induction and Shiga toxin release from E. coli O157:H7 and has a protective effect during infection

Apyrase decreases phage induction and Shiga toxin release from E. coli O157:H7 and has a protective effect during infection

Shiga toxin (Stx)-producing enterohemorrhagic Escherichia coli (EHEC) cause gastrointestinal infection and, in severe cases, hemolytic uremic syndrome which may lead to death. There is, to-date, no therapy for this infection. Stx induces ATP release from host cells and ATP signaling mediates its cyt...

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Bibliographic Details
Main Authors: Ida Arvidsson, Ashmita Tontanahal, Karl Johansson, Ann-Charlotte Kristoffersson, Sára Kellnerová, Michael Berger, Ulrich Dobrindt, Diana Karpman
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Gut Microbes
Subjects:
Enterohemorrhagic Escherichia coli
RecA
Shiga toxin
apyrase
intestine
mouse
Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2022.2122667
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https://www.tandfonline.com/doi/10.1080/19490976.2022.2122667

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