Modeling Lymphoma Angiogenesis, Lymphangiogenesis, and Vessel Co-Option, and the Effects of Inhibition of Lymphoma–Vessel Interactions with an αCD20-EndoP125A Antibody Fusion Protein

Modeling Lymphoma Angiogenesis, Lymphangiogenesis, and Vessel Co-Option, and the Effects of Inhibition of Lymphoma–Vessel Interactions with an αCD20-EndoP125A Antibody Fusion Protein

Lymphoma growth, progression, and dissemination require tumor cell interaction with supporting vessels and are facilitated through tumor-promoted angiogenesis, lymphangiogenesis, and/or lymphoma vessel co-option. Vessel co-option has been shown to be responsible for tumor initiation, metastasis, and...

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Bibliographic Details
Main Authors: Christian Elledge, Yu Zhang, Seung-Uon Shin, Hyun-Mi Cho, Sundaram Ramakrishnan, Ankita Sankar, Jennifer R. Chapman, Daniel Bilbao, Rathin Das, Hava Gil-Henn, Izidore S. Lossos, Joseph D. Rosenblatt
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Cells
Subjects:
lymphoma
mantle cell lymphoma
angiogenesis
lymphangiogenesis
vessel co-option
antibody fusion
Online Access:https://www.mdpi.com/2073-4409/13/22/1835
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