Species-specific gene regulatory network rewiring mediated by the GATA-type regulator NsdD in Aspergillus

Species-specific gene regulatory network rewiring mediated by the GATA-type regulator NsdD in Aspergillus

ABSTRACT The evolutionarily conserved GATA-type transcription factor (TF) NsdD regulates sexual and asexual development as well as secondary metabolism in various Aspergillus species. Despite its well-known multifunctionality, the mechanisms by which NsdD coordinates such diverse biological processe...

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Main Authors: Heungyun Moon, Mi-Kyung Lee, Junha Shin, Sung Chul Park, Julio C. Rivera Vazquez, Daniel Amador-Noguez, Nancy P. Keller, Hee-Soo Park, Kap-Hoon Han, Jae-Hyuk Yu
Format: Article
Language:English
Published: American Society for Microbiology 2025-08-01
Series:mBio
Subjects:
Aspergillus
GATA transcription factor
NsdD
development
metabolism
multiomics
Online Access:https://journals.asm.org/doi/10.1128/mbio.01181-25
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https://journals.asm.org/doi/10.1128/mbio.01181-25

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