Distinct Patterns of Smooth Muscle Phenotypic Modulation in Thoracic and Abdominal Aortic Aneurysms

Distinct Patterns of Smooth Muscle Phenotypic Modulation in Thoracic and Abdominal Aortic Aneurysms

Thoracic and abdominal aortic aneurysms (TAAs and AAAs, respectively) share morphological features but have distinct clinical and hereditary characteristics. Studies using bulk RNA comparisons revealed distinct patterns of gene expression in human TAA and AAA tissues. However, given the summative na...

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Bibliographic Details
Main Authors: Chien-Jung Lin, Campbell Keating, Robyn Roth, Yasar Caliskan, Mustafa Nazzal, Vernat Exil, Richard DiPaolo, Divya Ratan Verma, Kishore Harjai, Mohamed Zayed, Chieh-Yu Lin, Robert P. Mecham, Ajay K. Jain
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Journal of Cardiovascular Development and Disease
Subjects:
aortic aneurysm
smooth muscle cell
single-cell RNA sequencing
Online Access:https://www.mdpi.com/2308-3425/11/11/349
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