Effect of Oral Preanesthesic Sedation with Chlordiazepoxide and Haloperidol Before Anesthesia For Adult Male Bonnet Macaques (Macaca radiata)
Minimizing stress during the capture of wild animals is crucial for reducing morbidity and mortality. Oral premedicants have the potential to reduce stress during handling and ease the subsequent administration of anaesthetic drugs. The efficacy of premedication with chlordiazepoxide or haloperidol...
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| Format: | Article |
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Ferdowsi University of Mashhad
2024-12-01
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| Series: | The Iranian Journal of Veterinary Science and Technology |
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| Online Access: | https://ijvst.um.ac.ir/article_45627_1e9a88221b265f4e3c66556173ed6df2.pdf |
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| author | Kuskur Sannappa Naik Kamalesh Kumar George Chandy Serendran Sooryadas Dinesh Parathazathayi |
| author_facet | Kuskur Sannappa Naik Kamalesh Kumar George Chandy Serendran Sooryadas Dinesh Parathazathayi |
| author_sort | Kuskur Sannappa Naik Kamalesh Kumar |
| collection | DOAJ |
| description | Minimizing stress during the capture of wild animals is crucial for reducing morbidity and mortality. Oral premedicants have the potential to reduce stress during handling and ease the subsequent administration of anaesthetic drugs. The efficacy of premedication with chlordiazepoxide or haloperidol independently prior to midazolam-ketamine anaesthesia was evaluated in 12 male Bonnet Macaques. Animals were randomly divided into two groups of six animals each (n=6). Animals in Group I were administered chlordiazepoxide (10mg/kg) and animals in Group II were administered haloperidol (1mg/kg) orally, respectively. Temperament of each animal was recorded prior to premedication. Behavioural responses after pre-medication were assessed for 4 hours. Glucose and cortisol levels were assessed in venous blood samples collected after the induction of anaesthesia. Sedation was achieved in both groups of animals whereas the quality of sedation was comparatively better in Group II. Haloperidol-premedicated animals were easy to handle, but increased cortisol and glucose levels were recorded. Pre-medication with chlordiazepoxide and haloperidol produced optimum sedation to handle the Bonnet Macaques for inducing anaesthesia. |
| format | Article |
| id | doaj-art-7c46b0126b0e4e218d85ac890fb5caa8 |
| institution | Kabale University |
| issn | 2008-465X 2423-6306 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Ferdowsi University of Mashhad |
| record_format | Article |
| series | The Iranian Journal of Veterinary Science and Technology |
| spelling | doaj-art-7c46b0126b0e4e218d85ac890fb5caa82024-12-25T04:55:04ZengFerdowsi University of MashhadThe Iranian Journal of Veterinary Science and Technology2008-465X2423-63062024-12-0116411310.22067/ijvst.2024.88206.138245627Effect of Oral Preanesthesic Sedation with Chlordiazepoxide and Haloperidol Before Anesthesia For Adult Male Bonnet Macaques (Macaca radiata)Kuskur Sannappa Naik Kamalesh Kumar0George Chandy1Serendran Sooryadas2Dinesh Parathazathayi3Department of Animal Husbandry and Veterinary Services, Karnataka, India.Department of Veterinary Surgery and Radiology, College of Veterinary and Animal Sciences, Pookode, Wayanad-673 576, Kerala, India.Department of Veterinary Surgery and Radiology, College of Veterinary and Animal Sciences, Pookode, Wayanad-673 576, Kerala, India.Department of Veterinary Surgery and Radiology, College of Veterinary and Animal Sciences, Pookode, Wayanad-673 576, Kerala, India.Minimizing stress during the capture of wild animals is crucial for reducing morbidity and mortality. Oral premedicants have the potential to reduce stress during handling and ease the subsequent administration of anaesthetic drugs. The efficacy of premedication with chlordiazepoxide or haloperidol independently prior to midazolam-ketamine anaesthesia was evaluated in 12 male Bonnet Macaques. Animals were randomly divided into two groups of six animals each (n=6). Animals in Group I were administered chlordiazepoxide (10mg/kg) and animals in Group II were administered haloperidol (1mg/kg) orally, respectively. Temperament of each animal was recorded prior to premedication. Behavioural responses after pre-medication were assessed for 4 hours. Glucose and cortisol levels were assessed in venous blood samples collected after the induction of anaesthesia. Sedation was achieved in both groups of animals whereas the quality of sedation was comparatively better in Group II. Haloperidol-premedicated animals were easy to handle, but increased cortisol and glucose levels were recorded. Pre-medication with chlordiazepoxide and haloperidol produced optimum sedation to handle the Bonnet Macaques for inducing anaesthesia.https://ijvst.um.ac.ir/article_45627_1e9a88221b265f4e3c66556173ed6df2.pdforal premedicationchlordiazepoxidehaloperidolnon-human primatesbonnet macaquereduced stress |
| spellingShingle | Kuskur Sannappa Naik Kamalesh Kumar George Chandy Serendran Sooryadas Dinesh Parathazathayi Effect of Oral Preanesthesic Sedation with Chlordiazepoxide and Haloperidol Before Anesthesia For Adult Male Bonnet Macaques (Macaca radiata) The Iranian Journal of Veterinary Science and Technology oral premedication chlordiazepoxide haloperidol non-human primates bonnet macaque reduced stress |
| title | Effect of Oral Preanesthesic Sedation with Chlordiazepoxide and Haloperidol Before Anesthesia For Adult Male Bonnet Macaques (Macaca radiata) |
| title_full | Effect of Oral Preanesthesic Sedation with Chlordiazepoxide and Haloperidol Before Anesthesia For Adult Male Bonnet Macaques (Macaca radiata) |
| title_fullStr | Effect of Oral Preanesthesic Sedation with Chlordiazepoxide and Haloperidol Before Anesthesia For Adult Male Bonnet Macaques (Macaca radiata) |
| title_full_unstemmed | Effect of Oral Preanesthesic Sedation with Chlordiazepoxide and Haloperidol Before Anesthesia For Adult Male Bonnet Macaques (Macaca radiata) |
| title_short | Effect of Oral Preanesthesic Sedation with Chlordiazepoxide and Haloperidol Before Anesthesia For Adult Male Bonnet Macaques (Macaca radiata) |
| title_sort | effect of oral preanesthesic sedation with chlordiazepoxide and haloperidol before anesthesia for adult male bonnet macaques macaca radiata |
| topic | oral premedication chlordiazepoxide haloperidol non-human primates bonnet macaque reduced stress |
| url | https://ijvst.um.ac.ir/article_45627_1e9a88221b265f4e3c66556173ed6df2.pdf |
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