Loss of Surfactant Protein A Alters Perinatal Lung Morphology and Susceptibility to Hyperoxia-Induced Bronchopulmonary Dysplasia

Loss of Surfactant Protein A Alters Perinatal Lung Morphology and Susceptibility to Hyperoxia-Induced Bronchopulmonary Dysplasia

Bronchopulmonary dysplasia (BPD) is a condition of poor alveolar formation that causes chronic breathing impairment in infants born prematurely. Preterm lungs lack surfactant and are vulnerable to oxidative injuries driving the development of BPD. Our recent studies reported that surfactant protein...

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Bibliographic Details
Main Authors: Shaili Amatya, Matthew Lanza, Todd M. Umstead, Zissis C. Chroneos
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Antioxidants
Subjects:
bronchopulmonary dysplasia
hyperoxia
surfactant protein A (SP-A)
prematurity
neonatal
Online Access:https://www.mdpi.com/2076-3921/13/11/1309
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