Assessment of the physiological effects and safety of transpulmonary chemoembolization with doxorubicin on pulmonary tissue using a human-isolated lung perfusion model

Assessment of the physiological effects and safety of transpulmonary chemoembolization with doxorubicin on pulmonary tissue using a human-isolated lung perfusion model

Abstract Background Whole lung transpulmonary chemoembolization using a combination of doxorubicin (DXO) and degradable starch microspheres (DSM-TPCE) might be a promising treatment option in soft tissue sarcoma. To pave the way for clinical studies, this study aimed to evaluate the short-term effec...

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Main Authors: Alexis Slama, Hannah Steinberg, Stéphane Collaud, Özlem Okumus, Ralph-Axel Hilger, Sebastian Bauer, Hans-Ulrich Schildhaus, Clemens Aigner, Benedikt M. Schaarschmidt
Format: Article
Language:English
Published: SpringerOpen 2024-12-01
Series:European Radiology Experimental
Subjects:
Degradable starch microspheres
Embolization (therapeutic)
Lung
Perfusion
Sarcoma
Online Access:https://doi.org/10.1186/s41747-024-00532-3
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https://doi.org/10.1186/s41747-024-00532-3

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