Quantitative Magnetic Resonance Imaging of Enzyme Activity on the Cell Surface: In Vitro and In Vivo Monitoring of ADP-Ribosyltransferase 2 on T Cells
The objective of this study was to quantify enzymatic activity on the surface of T cells by magnetic resonance imaging (MRI) using R2 and R2* relaxometry. Lymphoma cells expressing adenosine diphosphate (ADP)-ribosyltransferase 2 (ART2) were incubated with increasing doses of its substrate etheno–ni...
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Main Authors: | Peter Bannas, Oliver Graumann, Philipp Balcerak, Kersten Peldschus, Michael Gerhard Kaul, Heinrich Hohenberg, Friedrich Haag, Gerhard Adam, Harald Ittrich, Friedrich Koch-Nolte |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2010-07-01
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Series: | Molecular Imaging |
Online Access: | https://doi.org/10.2310/7290.2010.00017 |
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