Quantitative Magnetic Resonance Imaging of Enzyme Activity on the Cell Surface: In Vitro and In Vivo Monitoring of ADP-Ribosyltransferase 2 on T Cells

The objective of this study was to quantify enzymatic activity on the surface of T cells by magnetic resonance imaging (MRI) using R2 and R2* relaxometry. Lymphoma cells expressing adenosine diphosphate (ADP)-ribosyltransferase 2 (ART2) were incubated with increasing doses of its substrate etheno–ni...

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Bibliographic Details
Main Authors: Peter Bannas, Oliver Graumann, Philipp Balcerak, Kersten Peldschus, Michael Gerhard Kaul, Heinrich Hohenberg, Friedrich Haag, Gerhard Adam, Harald Ittrich, Friedrich Koch-Nolte
Format: Article
Language:English
Published: SAGE Publishing 2010-07-01
Series:Molecular Imaging
Online Access:https://doi.org/10.2310/7290.2010.00017
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