Role of T cell exhaustion and tissue-resident memory T cells in the expression and prognosis of colorectal cancer

Abstract The tumour microenvironment (TME) is complex and dynamic, and changes significantly with tumour progression. Studying the evolving state of T cells, especially tumour-specific subsets, has become feasible. However, the roles of exhausted T cells (Tex) and pre-exhausted tissue-resident memor...

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Bibliographic Details
Main Authors: Han Wu, Pei-Wen Fan, Ya-Ning Feng, Cheng Chang, Ting Gui, Jia-bei Meng, Ruo-Zheng Wang
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-14409-x
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