Early Detection of Susceptibility to Acute Lung Inflammation by Molecular Imaging in Mice Exposed to Cigarette Smoke

Matrix metalloproteinases (MMPs) are extracellular proteolytic enzymes involved in acute lung inflammation in response to cigarette smoke exposure (CSE). We present the in vivo detection of MMP activity using a specific MMP-activatable, near-infrared, polymer-based proteolytic probe in strains of mi...

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Bibliographic Details
Main Authors: Sandra Pérez-Rial, Laura del Puerto-Nevado, Nicolás González-Mangado, Germán Peces-Barba
Format: Article
Language:English
Published: SAGE Publishing 2011-09-01
Series:Molecular Imaging
Online Access:https://doi.org/10.2310/7290.2011.00010
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