Exosomes derived from human umbilical cord mesenchymal stem cells ameliorate AKI after cardiac surgery by facilitating miR-21-5p targeting TEAD1

Exosomes derived from human umbilical cord mesenchymal stem cells ameliorate AKI after cardiac surgery by facilitating miR-21-5p targeting TEAD1

Background Acute kidney injury (AKI) is a common complication of cardiac surgery. Human umbilical cord mesenchymal stem cell (hUCMSC)-derived exosomes affect tissue damage and repair, and miR-21-5p reduces apoptosis and inflammation. However, miR-21-5p’s role in cardiac surgery remains unclear.Metho...

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Bibliographic Details
Main Authors: Zhengmin Li, Fang He, Shuyang Dai, Qingqing Yu, Chenchen Si, Fan Wu, Wenxin Zhao, Biyao Zhang, Poshi Xu
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Renal Failure
Subjects:
Human umbilical cord mesenchymal stem cells
exosomes
miR-21-5p
TEA domain family member 1
acute kidney injury
Online Access:https://www.tandfonline.com/doi/10.1080/0886022X.2025.2537797
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https://www.tandfonline.com/doi/10.1080/0886022X.2025.2537797

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