Risk assessment of the top 50 drugs associated with drug-induced orthostatic hypotension: a disproportionality analysis of the FAERS and JADER databases

Risk assessment of the top 50 drugs associated with drug-induced orthostatic hypotension: a disproportionality analysis of the FAERS and JADER databases

Abstract To use the FDA Adverse Event Reporting System (FAERS) database to identify drugs associated with orthostatic hypotension. Adverse event reports of orthostatic hypotension from Q1 2004 to Q3 2024 were obtained from the FAERS and JADER databases. We employed algorithms such as the reporting o...

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Bibliographic Details
Main Authors: Gaocan Ren, Xiansu Chi, Pingping Huang, Jinhui Zhang, Yanqiu Ding, Lijun Guo, Qinghua Shang, Xiaochang Ma
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Subjects:
Orthostatic hypotension
FDA
FAERS
Adverse drug events
Pharmacovigilance
Online Access:https://doi.org/10.1038/s41598-025-95021-x
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https://doi.org/10.1038/s41598-025-95021-x

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