A call to action to address critical flaws and bias in laboratory animal experiments and preclinical research
Abstract During the design of hypothesis-driven, comparative laboratory animal experiments, investigators must control for cage effects, ensure full blinding and full randomization while adhering to established experimental designs, notably variations of the Completely Randomized Design and the Rand...
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| Main Authors: | Hugh G. G. Townsend, Klaus Osterrieder, Murray D. Jelinski, Douglas W. Morck, Cheryl L. Waldner, William R. Cox, Volker Gerdts, Andrew A. Potter, Lorne A. Babiuk, James C. Cross |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-08-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-025-15935-4 |
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