A call to action to address critical flaws and bias in laboratory animal experiments and preclinical research

Abstract During the design of hypothesis-driven, comparative laboratory animal experiments, investigators must control for cage effects, ensure full blinding and full randomization while adhering to established experimental designs, notably variations of the Completely Randomized Design and the Rand...

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Bibliographic Details
Main Authors: Hugh G. G. Townsend, Klaus Osterrieder, Murray D. Jelinski, Douglas W. Morck, Cheryl L. Waldner, William R. Cox, Volker Gerdts, Andrew A. Potter, Lorne A. Babiuk, James C. Cross
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-15935-4
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