Multiplex Eukaryotic Transcription (In)activation: Timing, Bursting and Cycling of a Ratchet Clock Mechanism.

Activation of eukaryotic transcription is an intricate process that relies on a multitude of regulatory proteins forming complexes on chromatin. Chromatin modifications appear to play a guiding role in protein-complex assembly on chromatin. Together, these processes give rise to stochastic, often bu...

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Bibliographic Details
Main Authors: Katja N Rybakova, Frank J Bruggeman, Aleksandra Tomaszewska, Martijn J Moné, Carsten Carlberg, Hans V Westerhoff
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-04-01
Series:PLoS Computational Biology
Online Access:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1004236&type=printable
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