A High-Affinity Monoclonal Antibody Against the Pancreatic Ductal Adenocarcinoma Target, Anterior Gradient-2 (AGR2/PDIA17)

A High-Affinity Monoclonal Antibody Against the Pancreatic Ductal Adenocarcinoma Target, Anterior Gradient-2 (AGR2/PDIA17)

Background/Objectives: Anterior Gradient-2 (AGR2/PDIA17) is a member of the protein disulfide isomerase (PDI) family of oxidoreductases. AGR2 is up-regulated in several solid tumors, including pancreatic ductal adenocarcinoma (PDAC). Given the dire need for new therapeutic options for PDAC patients,...

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Bibliographic Details
Main Authors: Reeder M. Robinson, Leticia Reyes, Benjamin N. Christopher, Ravyn M. Duncan, Rachel A. Burge, Julie Siegel, Patrick Nasarre, Pingping Wang, John P. O’Bryan, G. Aaron Hobbs, Nancy Klauber-DeMore, Nathan G. Dolloff
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Antibodies
Subjects:
AGR2
PDIA17
anterior gradient-2
protein disulfide isomerase
pancreatic cancer
PDAC
Online Access:https://www.mdpi.com/2073-4468/13/4/101
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https://www.mdpi.com/2073-4468/13/4/101

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